Understanding Telomeres in Telomerase Analysis Technology
The use of telomerase analysis technology (TAT) is becoming rampant in this day and age. In a nutshell, this test is a biomarker that is capable of determining risks and early prognosis o of certain illnesses like cancer. The process involves a comprehensive analysis and evaluation of the length of the telomere. The length of telomeres is a key factor in determining age-related diseases. Telomeres may be used as an individual biomarker or in combination with other biomarkers. The fact that you can get telomeres from multiple samples makes the whole process much more convenient compared to other biomarkers. To understand more about telomerase analysis technology, it helps if you get to know telomeres first and foremost. For some noteworthy facts about telomeres, find out here and get info.
As mentioned above, the length of your telomeres is associated with age-related disorders. Aging is a normal life occurrence. Until this time, there are many questions about aging like its causes and why a person ages that even scientists are truly baffled. Many theories are published year after year, such DNA being affected and damaged by oxidative stress. Should glucose be blamed as well? What about the cells of the body just all along following a biological timetable that is pre-programmed? Perhaps aging is caused by a combination of these factors and even more that people can’t seem to understand.
One of the most highly supported theories of aging will have to be one that links the natural process to telomeres. Telomeres are tiny protective caps that you can find at ends of DNA molecules that form your chromosomes. Their main responsibility is to stop the ends of chromosomes from sticking together or fraying.
Telomeres also play a crucial role in ensuring that a person’s DNA is properly copied when cells divide. Unfortunately, there are some instances in DNA replication that some of the building blocks of DNA or nucleotides found at the end of the strand are unable to make it into the new copy of the DNA. The result is often a loss of some of the genetic information. DNA strands naturally shorter with every division of the cells.
So, how come cells still have some DNA left after the division they’ve undergone? This is where the role of telomeres comes in. When it comes to telomeres, they have a similar DNA sequence that is repeated time and time again, making them somehow disposable after all this repetition. They make sure to keep the rest of the DNA protected. Even if they get shorter time and time again, they will make sure not to lose your genetic information.
When telomeres shorten, some scientists believe that it is one of the factors that cause aging of the cells. Cells cannot divide like they should when they have too short telomeres. If they reach a crucial point, the cell now becomes inactive that either make them accumulate damage they can’t fix or they simply die.